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Thesis

Investigating the content and function of stress-induced extracellular vesicles in colorectal cancer

Abstract:

Despite advances in detection and treatment, the incidence of colorectal cancer (CRC), particularly in those under 40 years of age is increasing, and survival from metastatic disease remains very low. Adaptation of tumour cells to microenvironmental stresses and anti-cancer therapies is a key mechanism driving tumour progression and resistance. Extracellular vesicles (EVs) are nanosized membrane-bound vesicles, which carry rich bioactive cargoes that are able to influence and reprogramme r...

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Division:
MSD
Department:
Physiology Anatomy & Genetics
Sub department:
Physiology Anatomy & Genetics
Research group:
Goberdhan Group
Oxford college:
Magdalen College
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
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Programme:
CRUK Oxford Centre Clinical Research Training Fellowship
Grant:
C2195/A25190
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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