Journal article
MEF2 transcription factors are key regulators of sprouting angiogenesis
- Abstract:
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Angiogenesis, the fundamental process by which new blood vessels form from existing ones, depends on precise spatial and temporal gene expression within specific compartments of the endothelium. However, the molecular links between pro-angiogenic signals and downstream gene expression remain unclear. During sprouting angiogenesis, the specification of endothelial cells into the tip cells that lead new blood vessel sprouts is coordinated by VEGFA and Dll4/Notch signaling, and requires high lev...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 2.0MB)
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- Publisher copy:
- 10.1101/gad.290619.116
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Authors
Funding
+ Medical Research Council
More from this funder
Funding agency for:
Sacilotto, N
Grant:
PG/10/83/28610
+ British Heart Foundation
More from this funder
Funding agency for:
Sacilotto, N
Grant:
PG/10/83/28610
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Bibliographic Details
- Publisher:
- Cold Spring Harbor Laboratory Press Publisher's website
- Journal:
- Genes and Development Journal website
- Volume:
- 30
- Pages:
- 2297-2309
- Publication date:
- 2016-01-01
- Acceptance date:
- 2016-09-29
- DOI:
- EISSN:
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1549-5477
- ISSN:
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0890-9369
- Source identifiers:
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648331
Item Description
- Keywords:
- Pubs id:
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pubs:648331
- UUID:
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uuid:4dfdbb0d-4a9e-4518-bc0d-60e5a4405764
- Local pid:
- pubs:648331
- Deposit date:
- 2016-10-07
Terms of use
- Copyright holder:
- © Sacilotto, et al
- Copyright date:
- 2016
- Notes:
-
© 2016 Sacilotto et al.; Published by Cold Spring Harbor Laboratory Press
This article, published in Genes & Development, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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