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Journal article

Differential anti-chemokine activity of Amblyomma variegatum adult ticks during blood-feeding.

Abstract:

Ticks secrete a cocktail of immunomodulatory molecules in their saliva during blood-feeding, including chemokine-binding factors that help control the activity of host immunocompetent cells. Here we demonstrate differential dynamics of anti IL-8 (CXCL8), MCP-1 (CCL2), MIP-1 (CCL3), RANTES (CCL5) and eotaxin (CCL11) activities in salivary gland extracts of adult Amblyomma variegatum. Unfed male and female ticks showed activity against all the chemokines except CCL5; anti-CCL11 activity was par...

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Publication status:
Published

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Journal:
Parasite immunology
Volume:
29
Issue:
4
Pages:
169-177
Publication date:
2007-04-01
DOI:
EISSN:
1365-3024
ISSN:
0141-9838
Source identifiers:
404180
Language:
English
Keywords:
Pubs id:
pubs:404180
UUID:
uuid:4ef1db4b-2e92-48aa-8d86-a9e1cd6730b6
Local pid:
pubs:404180
Deposit date:
2013-11-16

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