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Thesis

Epigenetic regulation of chronological and replicative longevity in Saccharomyces cerevisiae

Abstract:

Ageing and senescence remain among the most intriguing questions in biology. Saccharomyces cerevisiae has become well established as a fertile model system for the investigation of ageing. Remarkable conservation has been found to exist between interventions extending lifespan in higher animals and yeast – genetic, chemical, and nutritional – suggesting a network of common regulatory pathways controlling large-scale shifts in gene expression involved in senescence. While it has been ...

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Division:
MSD
Department:
Biochemistry
Role:
Author

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Department:
Biochemistry
Role:
Supervisor
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Funding agency for:
Mellor, E
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
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UUID:
uuid:4f59670e-5783-4548-b553-abe1c1c0a9ab
Deposit date:
2016-09-29

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