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Thesis

The role and regulation of Asterless in the centrosome cycle

Abstract:

Centrosomes are the main microtubule organizing centres in animal cells and are formed by a pair of centrioles together with surrounding pericentriolar material (PCM). Cycling cells duplicate their centrosomes strictly once per cell cycle. This process is driven by the semi-conservative duplication of the centrioles that are found at the centrosome core. During the exit from mitosis the two centrioles within the single inherited centrosome separate, and upon the start of S-phase each of th...

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Oxford college:
Lincoln College
Role:
Author

Contributors

Division:
MPLS
Department:
Doctoral Training Centre - MPLS
Role:
Supervisor
More from this funder
Funding agency for:
Novak, Z
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:4fadaef1-8c9e-4c70-ac59-47f35af3988e
Local pid:
ora:11906
Deposit date:
2015-07-27

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