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Magnesium efflux from Drosophila Kenyon cells is critical for normal and diet-enhanced long-term memory

Abstract:

Dietary magnesium (Mg2+) supplementation can enhance memory in young and aged rats. Memory-enhancing capacity was largely ascribed to increases in hippocampal synaptic density and elevated expression of the NR2B subunit of the NMDA-type glutamate receptor. Here we show that Mg2+ feeding also enhances long-term memory in Drosophila. Normal and Mg2+-enhanced fly memory appears independent of NMDA receptors in the mushroom body and instead requires expression of ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.7554/elife.61339

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Role:
Author
ORCID:
0000-0003-2401-7969
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Publisher:
eLife Sciences Publications Publisher's website
Journal:
eLife Journal website
Volume:
9
Article number:
e61339
Pages:
1-113
Publication date:
2020-11-26
Acceptance date:
2020-11-25
DOI:
EISSN:
2050-084X
Pmid:
33242000
Language:
English
Keywords:
Pubs id:
1147298
Local pid:
pubs:1147298
Deposit date:
2021-02-22

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