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Journal article : Review

Inflammasome-mediated immunogenicity of clinical and experimental vaccine adjuvants

Abstract:

In modern vaccines, adjuvants can be sophisticated immunological tools to promote robust and long-lasting protection against prevalent diseases. However, there is an urgent need to improve immunogenicity of vaccines in order to protect mankind from life-threatening diseases such as AIDS, malaria or, most recently, COVID-19. Therefore, it is important to understand the cellular and molecular mechanisms of action of vaccine adjuvants, which generally trigger the innate immune system to enhance ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3390/vaccines8030554

Authors


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Role:
Author
ORCID:
0000-0003-2412-385X
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Role:
Author
ORCID:
0000-0003-0693-6101
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Role:
Author
ORCID:
0000-0002-8115-6597
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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
ORCID:
0000-0003-1441-1727
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
ORCID:
0000-0002-7984-1317
Publisher:
MDPI Publisher's website
Journal:
Vaccines Journal website
Volume:
8
Issue:
3
Article number:
554
Publication date:
2020-09-22
Acceptance date:
2020-09-18
DOI:
EISSN:
2076-393X
Pmid:
32971761
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1134993
Local pid:
pubs:1134993
Deposit date:
2020-10-10

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