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Journal article : Review

Mechanisms and roles of mitochondrial localisation and dynamics in neuronal function

Abstract:

Neurons are highly polarised, complex and incredibly energy intensive cells, and their demand for ATP during neuronal transmission is primarily met by oxidative phosphorylation by mitochondria. Thus, maintaining the health and efficient function of mitochondria is vital for neuronal integrity, viability and synaptic activity. Mitochondria do not exist in isolation, but constantly undergo cycles of fusion and fission, and are actively transported around the neuron to sites of high energy deman...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1042/ns20200008

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
ORCID:
0000-0002-7974-6803
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Role:
Author
ORCID:
0000-0002-8904-5795
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Role:
Author
ORCID:
0000-0003-3589-8335
More by this author
Role:
Author
ORCID:
0000-0002-8115-8592
Publisher:
Portland Press Publisher's website
Journal:
Neuronal Signaling Journal website
Volume:
4
Issue:
2
Article number:
NS20200008
Place of publication:
England
Publication date:
2020-06-01
Acceptance date:
2020-05-15
DOI:
EISSN:
2059-6553
ISSN:
2059-6553
Pmid:
32714603
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1159768
Local pid:
pubs:1159768
Deposit date:
2021-02-02

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