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Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion

Abstract:

Salmonella enterica represent a major disease burden worldwide. S. enterica serovar Typhi (S. Typhi) is responsible for potentially life-threatening Typhoid fever affecting 10.9 million people annually. While non-typhoidal Salmonella (NTS) serovars usually trigger self-limiting diarrhoea, invasive NTS bacteraemia is a growing public health challenge. Dendritic cells (DCs) are key professional antigen presenting cells of the human immune system. The ability of pathogenic bacteria to subvert DC...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s42003-022-03038-z

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Role:
Author
ORCID:
0000-0002-3407-2796
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Role:
Author
ORCID:
0000-0002-6262-755X
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Publisher:
Springer Nature Publisher's website
Journal:
Communications Biology Journal website
Volume:
5
Issue:
1
Article number:
111
Place of publication:
England
Publication date:
2022-02-04
Acceptance date:
2021-12-15
DOI:
EISSN:
2399-3642
Pmid:
35121793
Language:
English
Keywords:
Pubs id:
1238504
Local pid:
pubs:1238504
Deposit date:
2022-07-30

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