Cancer immunotherapy: Killers on sterols.
The dream of stimulating the body's immune response to fight cancer has become a reality in the past decade. Several potent drugs have been clinically approved that block inhibitory checkpoints in the immune system, boosting the ability of the system's T cells to mount responses against a range of cancers1. Furthermore, patients' own T cells have been successfully genetically engineered to attack blood-cancer cells2. Although these studies have established the immune system as a powerful ally...Expand abstract
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- Peer review status:
- Peer reviewed
(Accepted manuscript, pdf, 240.2KB)
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- Copyright holder:
- Michael Dustin
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- Author(s) retain copyright; published by Nature Publishing Group under license. This is the accepted manuscript version of the article. The final version is available online from Nature Publishing Group at: [10.1038/nature17310].
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