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Thesis

Ultrasound-triggered drug release from liposomes using nanoscale cavitation nuclei

Abstract:

Side effects of current chemotherapeutics limit their use in cancer therapy. Although many current drugs are highly toxic and potent, the effects they have on non-cancerous tissue are unbearable for patients. Targeting these drugs may provide a means to restrict their toxic effects to only cancer tissue while leaving healthy tissue unaffected. This approach requires that the drug is only available in cancer tissue, which has been achieved here by encapsulating drugs into liposomal nano-cap...

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Research group:
BUBBL - biomedical ultrasonics, biotherapy and biopharmaceuticals laboratory
Oxford college:
Wolfson College
Role:
Author
More by this author
Division:
MPLS
Department:
Engineering Science
Role:
Author

Contributors

Division:
MPLS
Department:
Engineering Science
Role:
Supervisor
Division:
MPLS
Department:
Engineering Science
Role:
Supervisor
More from this funder
Funding agency for:
Graham, S
Grant:
WT088877/Z/09/Z
More from this funder
Funding agency for:
Graham, S
Grant:
WT088877/Z/09/Z
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK

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