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Thesis

Development and application of asymmetric C-N bond formation

Abstract:

A synthetic investigation on the chemistry of cyclotryptamine derived natural products, with a particular focus on the synthesis of the trimeric-alkaloid, hodgkinsine. Methodology has been developed to tackle this complex natural product which utilises a desymmetrization approach; this strategy hinges on the development and applications of asymmetric C-N bond forming reactions.

Chapter one examines elements of symmetry in natural products, looking in particular at the synthesis of co...

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Research group:
Dr. M. C. Willis
Oxford college:
Brasenose College
Role:
Author

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Role:
Supervisor
Role:
Sponsor
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK

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