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Using genomic information to guide ibrutinib treatment decisions in chronic lymphocytic leukaemia: a cost-effectiveness analysis

Abstract:
Background: Genomic tests may improve the stratification of patients to receive new therapies in several disease areas. However, the use of expensive targeted therapies can impact on the costeffectiveness of these tests. This study presents an economic evaluation of genomic testing in chronic lymphocytic leukaemia (CLL) in the context of the UK National Health Service (NHS). Methods: Cost-effectiveness and cost-utility analyses (using life-years and quality-a... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s40273-017-0519-z

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Population Health
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Population Health
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
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Funding agency for:
Wordsworth, S
Grant:
Biomedical Research Centre, Oxford
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Funding agency for:
Taylor, J
Grant:
Biomedical Research Centre, Oxford
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Funding agency for:
Schuh, A
Grant:
Biomedical Research Centre, Oxford
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Funding agency for:
Knight, S
Grant:
Biomedical Research Centre, Oxford
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Publisher:
Springer International Publishing Publisher's website
Journal:
PharmacoEconomics Journal website
Volume:
35
Issue:
8
Pages:
845–858
Publication date:
2017-07-31
Acceptance date:
2017-05-11
DOI:
EISSN:
1179-2027
ISSN:
1170-7690
Keywords:
Pubs id:
pubs:694746
UUID:
uuid:51309c26-a402-43c0-94af-3f523dc004d6
Local pid:
pubs:694746
Deposit date:
2017-05-15

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