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Journal article

Immunomodulation in multiple sclerosis: promises and pitfalls

Abstract:

Multiple sclerosis (MS) afflicts about 2.5 million people globally and poses a major personal and socioeconomic burden. The recognition of MS as an inflammatory disease, characterized by infiltration of immune cells into the central nervous system, has spurred research into the autoimmune etiology of the condition and has provided the rationale for its treatment through immunomodulation. Experience with immunotherapies in MS to date has suggested a disparity between the observed immune cell i...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.coi.2017.08.013

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
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Grant:
100308/Z/12/Z to L.F
More from this funder
Grant:
OCAY-15-520 to L.F
Publisher:
Elsevier Publisher's website
Journal:
Current Opinion in Immunology Journal website
Volume:
49
Pages:
37-43
Publication date:
2017-09-18
DOI:
EISSN:
1879-0372
ISSN:
0952-7915
Pmid:
28926740
Source identifiers:
730108
Language:
English
Pubs id:
pubs:730108
UUID:
uuid:5199e437-5a5c-48cb-89b4-57dd858d8ac1
Local pid:
pubs:730108
Deposit date:
2017-12-05

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