Journal article icon

Journal article

Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure

Abstract:

The archaeal RNA polymerase (RNAP) shares structural similarities with eukaryotic RNAP II but requires a reduced subset of general transcription factors for promoter-dependent initiation. To deepen our knowledge of cellular transcription, we have determined the structure of the 13-subunit DNA-directed RNAP from Sulfolobus shibatae at 3.35 Å resolution. The structure contains the full complement of subunits, including RpoG/Rpb8 and the equivalent of the clamp-head and jaw domains of t...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pbio.1000102

Authors


More by this author
Institution:
Harvard Medical School, Boston, USA
Department:
Howard Hughes Medical Institute
Role:
Author
More by this author
Institution:
Howard Hughes Medical Institute, Harvard University, USA
Role:
Author
More by this author
Institution:
Yale University, USA
Department:
Howard Hughes Medical Institute
Role:
Author
More by this author
Institution:
Harvard Medical School, Boston, USA
Department:
Howard Hughes Medical Institute
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford Protein Production Facility
Role:
Author
Expand authors...

Contributors

Institution:
Vanderbilt University, USA
Role:
Editor
More from this funder
Funding agency for:
Abrescia, N
Expand funders...
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Biology Journal website
Volume:
7
Issue:
5
Article number:
e1000102
Publication date:
2009-05-01
DOI:
EISSN:
1545-7885
ISSN:
1544-9173
Language:
English
Keywords:
Subjects:
UUID:
uuid:526dfd47-90c0-4279-a961-04a573f0e71d
Local pid:
ora:2807
Deposit date:
2009-06-04

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP