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Thesis

Functional genomics of variation in response to infection: insights into severe sepsis and common variable immune deficiency disorders

Abstract:

Functional genomics uses high throughput genome-wide technologies to investigate the functional consequences of genetic variants on gene expression and protein products. In the context of disease, using integrative functional genomic approaches to understand the genetic variation which underlies disease susceptibility and aetiology may contribute to better diagnosis, treatment and prevention. This thesis investigated genetic determinants of variation in response to infection by applying a ...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Research group:
Julian Knight
Oxford college:
Hertford College
Role:
Author

Contributors

Division:
MSD
Department:
NDM
Role:
Supervisor
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Funding agency for:
Davenport, E
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:528edf20-f948-4a9c-aa23-1e295b11c8cc
Local pid:
ora:10706
Deposit date:
2015-03-24

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