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Thesis

Development of advanced three-dimensional tumour models for anti-cancer drug testing

Abstract:

Animal testing is still the common method to test the efficacy of new drugs, but tissue engineered in vitro models are becoming more acceptable for replacing and reducing animal testing in anti-cancer drug screening by developing in vitro three-dimensional (3D) tumour models for anti-cancer drug testing. In this study, three-dimensional (3D) culture methods were developed to mimic the tumour microenvironment. 3D culturing is to seed, maintain and expand cultured cells in three-dimens...

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Research group:
Institute of Biomedical Engineering
Oxford college:
Linacre College
Role:
Author

Contributors

Division:
MPLS
Department:
Engineering Science
Role:
Supervisor
Division:
MPLS
Department:
Engineering Science
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK

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