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Journal article

mTOR signalling and metabolic regulation of T cell differentiation.

Abstract:

T cells constantly monitor energy status and nutrient levels in order to adjust metabolic pathways according to their nutritional status and other environmental stimuli. It is increasingly evident that the regulation of cellular metabolism is tightly coupled to T cell differentiation that ultimately determines the cellular fate. The mammalian target of Rapamycin (mTOR) pathway has emerged as a key player in sensing these nutritional/energetic signals and in addition, acts as a major integrato...

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Publication status:
Published

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Publisher copy:
10.1016/j.coi.2010.08.010

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Current opinion in immunology
Volume:
22
Issue:
5
Pages:
655-661
Publication date:
2010-10-01
DOI:
EISSN:
1879-0372
ISSN:
0952-7915
Source identifiers:
73302
Language:
English
Keywords:
Pubs id:
pubs:73302
UUID:
uuid:53c27811-88d2-44d0-9cdb-3cea17fbc70a
Local pid:
pubs:73302
Deposit date:
2012-12-19

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