Journal article
Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis.
- Abstract:
-
Nuclear factor kappa B (NF-kappa B) activation has been observed in human atherosclerotic plaques and is enhanced in unstable coronary plaques, but whether such activation has a protective or pathophysiological role remains to be determined. We addressed this question by developing a short-term culture system of cells isolated from human atherosclerotic tissue, allowing efficient gene transfer to directly investigate signaling pathways in human atherosclerosis. We found that NF-kappa B is act...
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- Publication status:
- Published
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- Publisher copy:
- 10.1073/pnas.0401060101
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Authors
Bibliographic Details
- Journal:
- Proceedings of the National Academy of Sciences of the United States of America
- Volume:
- 101
- Issue:
- 15
- Pages:
- 5634-5639
- Publication date:
- 2004-04-01
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
- Source identifiers:
-
224586
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:224586
- UUID:
-
uuid:5416c7b0-1518-401c-bca4-bf59bf9555de
- Local pid:
- pubs:224586
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2004
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