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Identification and separation of DNA mixtures using peak area information.

Abstract:

We introduce a new methodology, based upon probabilistic expert systems, for analysing forensic identification problems involving DNA mixture traces using quantitative peak area information. Peak area is modelled with conditional Gaussian distributions. The expert system can be used for ascertaining whether individuals, whose profiles have been measured, have contributed to the mixture. It can also be used to predict DNA profiles of unknown contributors by separating the mixture into its indi...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Role:
Author
Journal:
Forensic science international
Volume:
166
Issue:
1
Pages:
28-34
Publication date:
2007-02-01
DOI:
EISSN:
1872-6283
ISSN:
0379-0738
Source identifiers:
97485
Language:
English
Keywords:
Pubs id:
pubs:97485
UUID:
uuid:544ff5f5-a91a-4846-99eb-6c32013be723
Local pid:
pubs:97485
Deposit date:
2012-12-19

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