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Tmem176B and Tmem176A are associated with the immature state of dendritic cells.

Abstract:

DCs play a central role in the development of innate and adaptive immunity but also in the induction and maintenance of immune tolerance. Identification of factors that govern DC activation, their maturation state, and their capacity to induce proinflammatory or tolerogeneic responses therefore represents a crucial aim of research. We previously identified a new molecule, Tmem176B (which we named TORID initially), as highly expressed in a model of allograft tolerance in the rat. We showed tha...

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Publication status:
Published

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Publisher copy:
10.1189/jlb.1109738

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
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Journal:
Journal of leukocyte biology
Volume:
88
Issue:
3
Pages:
507-515
Publication date:
2010-09-01
DOI:
EISSN:
1938-3673
ISSN:
0741-5400
Source identifiers:
55402

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