Journal article : Review
Pancreatic cancer microenvironment and cellular composition: Current understandings and therapeutic approaches
- Abstract:
-
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal human solid tumors, despite great efforts in improving therapeutics over the past few decades. In PDAC, the distinct characteristic of the tumor microenvironment (TME) is the main barrier for developing effective treatments. PDAC TME is characterized by a dense stroma, cancer-associated fibroblasts, and immune cells populations that crosstalk to the subpopulations of neoplastic cells that include cancer stem cells (CSCs). ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Bibliographic Details
- Publisher:
- MDPI Publisher's website
- Journal:
- Cancers Journal website
- Volume:
- 13
- Issue:
- 19
- Article number:
- 5028
- Publication date:
- 2021-10-08
- Acceptance date:
- 2021-10-06
- DOI:
- EISSN:
-
2072-6694
- Pmid:
-
34638513
Item Description
- Language:
- English
- Keywords:
- Subtype:
- Review
- Pubs id:
-
1204205
- Local pid:
- pubs:1204205
- Deposit date:
- 2021-11-29
Terms of use
- Copyright holder:
- Truong and Pauklin.
- Copyright date:
- 2021
- Rights statement:
- © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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