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A new approach to find biomarkers in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) by single-cell Raman micro-spectroscopy

Abstract:

Chronic fatigue syndrome (CFS), also called myalgic encephalomyelitis (ME), is a debilitating disorder characterized by physical and mental exhaustion. Mitochondrial and energetic dysfunction has been investigated in CFS patients due to a hallmark relationship with fatigue, however, no consistent conclusion has yet been achieved. Single-cell Raman spectra (SCRS) are label-free biochemical profiles, indicating phenotypic fingerprints of single cells. In this study, we applied a new approach us...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/C8AN01437J

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Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
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Institution:
University of Oxford
Division:
Medical Sciences
Department:
Nuffield Department of Women's and Reproductive Health
Role:
Author
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Institution:
University of Oxford
Division:
Medical Sciences
Department:
Nuffield Department of Women's and Reproductive Health
Role:
Author
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Funding agency for:
Potter, M
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Funding agency for:
Morten, K
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Funding agency for:
Huang, W
Grant:
NE/M002934/1
More from this funder
Funding agency for:
Huang, W
Grant:
NE/M002934/1
Publisher:
Royal Society of Chemistry Publisher's website
Journal:
Analyst Journal website
Volume:
144
Issue:
3
Pages:
913-920
Publication date:
2018-08-22
Acceptance date:
2018-08-21
DOI:
EISSN:
1364-5528
ISSN:
0003-2654
Source identifiers:
909301
Keywords:
Pubs id:
pubs:909301
UUID:
uuid:56069cef-320f-43ad-b970-20c1fdced6e4
Local pid:
pubs:909301
Deposit date:
2018-08-22

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