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The immune synapse: past, present, and future

Abstract:

Immunological synapses are specialized cell-cell junctions characterized by (1) close apposition of the immune cell membrane with the membrane of another cell driven by adaptive or innate immune recognition, (2) adhesion, (3) stability, and (4) directed secretion. This phenomenon was first recognized in the 1970s and the early 1980s through electron microscopy of ex vivo functioning immune cells. Progressive advances in fluorescence microscopy and molecular im...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/978-1-4939-6881-7_1

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
Publisher:
Humana Press Publisher's website
Volume:
1584
Pages:
1-5
Host title:
Methods in Molecular Biology
Publication date:
2017-03-03
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
Source identifiers:
685959
ISBN:
9781493968794
Language:
English
Keywords:
Pubs id:
pubs:685959
UUID:
uuid:5646d567-403d-449c-9f5f-caf8c38fe350
Local pid:
pubs:685959
Deposit date:
2017-03-22

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