Subthalamic deep brain stimulation sweet spots and hyperdirect cortical connectivity in Parkinson's disease
Firstly, to identify subthalamic region stimulation clusters that predict maximum improvement in rigidity, bradykinesia and tremor, or emergence of side-effects; and secondly, to map-out the cortical fingerprint, mediated by the hyperdirect pathways which predict maximum efficacy.
High angular resolution diffusion imaging in twenty patients with advanced Parkinson's disease was acquired prior to bilateral subthalamic nucleus deep brain stimulati...Expand abstract
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- Peer reviewed
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- Akram et al
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- © 2017 Published by Elsevier Inc.
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