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Journal article

Subthalamic deep brain stimulation sweet spots and hyperdirect cortical connectivity in Parkinson's disease

Abstract:

Objectives

Firstly, to identify subthalamic region stimulation clusters that predict maximum improvement in rigidity, bradykinesia and tremor, or emergence of side-effects; and secondly, to map-out the cortical fingerprint, mediated by the hyperdirect pathways which predict maximum efficacy.

Methods

High angular resolution diffusion imaging in twenty patients with advanced Parkinson's disease was acquired prior to bilateral subthalamic nucleus deep brain stimulati...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MPLS Division
Department:
Doctoral Training Centre - MPLS
Role:
Author
ORCID:
0000-0003-4735-5776
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Oxford college:
Linacre College
Role:
Author
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National Institute for Health Research More from this funder
Brain Research Trust More from this funder
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Publisher:
Elsevier Publisher's website
Journal:
NeuroImage Journal website
Volume:
158
Pages:
332-345
Publication date:
2017-07-12
Acceptance date:
2017-07-09
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
Pmid:
28711737
Source identifiers:
709528

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