Thesis
E2F7: a member of the E2F family with a novel mechanism of transcriptional repression
- Abstract:
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The mammalian E2F family of transcription factors plays a crucial role in the regulation of cellular proliferation, apoptosis and differentiation. E2F7 and E2F8 are the most recently identified family members and have unusual features that distinguish them from other members in the E2F family, including two distinct DNA-binding domains that bind to DNA in a DP-independent manner. E2F7 and E2F8 have been shown to be transcriptional repressors. However, the mechanism by which E2F7 represses ...
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Funding
Bibliographic Details
- Publication date:
- 2012
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:5694f75b-0e73-493c-a6bd-da10793aded3
- Local pid:
- ora:6678
- Deposit date:
- 2013-01-28
Terms of use
- Copyright holder:
- Poli Xenia Kesoglidou
- Copyright date:
- 2012
- Notes:
- This thesis is not currently available via ORA.
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