Journal article
Navigating critical challenges associated with immunopeptidomics-based detection of proteasomal spliced peptide candidates
- Abstract:
-
Within the tumor immunology community, the topic of proteasomal spliced peptides (PSP) has generated a great deal of controversy. In the earliest reports, careful biological validation led to the conclusion that proteasome-catalyzed peptide splicing was a rare event. To date, six PSPs have been validated biologically. However, the advent of algorithms to identify candidate PSPs in mass spectrometry data challenged this notion, with several studies concluding that the frequency of spliced pept...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1158/2326-6066.cir-21-0727
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Authors
Bibliographic Details
- Publisher:
- American Association for Cancer Research Publisher's website
- Journal:
- Cancer Immunology Research Journal website
- Volume:
- 10
- Issue:
- 3
- Pages:
- 275–284
- Publication date:
- 2022-02-01
- Acceptance date:
- 2022-01-14
- DOI:
- EISSN:
-
2326-6074
- ISSN:
-
2326-6066
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1237535
- Local pid:
- pubs:1237535
- Deposit date:
- 2022-02-16
Terms of use
- Copyright holder:
- American Association for Cancer Research
- Copyright date:
- 2022
- Rights statement:
- © 2022 American Association for Cancer Research
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