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Thesis

Discovery of a conserved Plasmodium antigen on the surface of malaria-infected red blood cells

Abstract:

During its intraerythrocytic stages (IE), Plasmodium falciparum, the causative agent of the deadliest human malaria, remodels the host red cell membrane with a poorly defined assortment of parasite-­encoded proteins that undergo antigenic variation. Despite the requirement for immunologic stealth, exported parasite proteins also mediate strain-independent functions such as endothelial sequestration that are critical for parasite survival and pathogenesis.

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Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
Prof. Chris Newbold
Oxford college:
Green Templeton College
Role:
Author
More by this author
Division:
MSD
Department:
NDM
Role:
Author

Contributors

Division:
MSD
Department:
NDM
Role:
Supervisor
Division:
MSD
Department:
NDM
Role:
Supervisor
National Institutes of Health More from this funder
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:592769fc-2628-4c6e-9a68-99060fb8c091
Local pid:
ora:8605
Deposit date:
2014-06-13

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