Journal article
Antibody opsonization enhances MAIT cell responsiveness to bacteria via a TNF-dependent mechanism
- Abstract:
-
Mucosal-associated invariant T (MAIT) cells are an abundant human T cell subset with anti-microbial properties. They can respond to bacteria presented via antigen-presenting cells (APCs) such as macrophages, which present bacterially derived ligands from the riboflavin synthesis pathway on MR1. Moreover, MAIT cells are also highly responsive to cytokines which enhance and even substitute for TCR-mediated signaling. The mechanisms leading to an efficient presentation of bacteria to MAIT cells ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Funding
Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Immunology and Cell Biology Journal website
- Volume:
- 97
- Issue:
- 6
- Pages:
- 538-551
- Publication date:
- 2019-01-29
- Acceptance date:
- 2019-01-23
- DOI:
- EISSN:
-
1440-1711
- ISSN:
-
0818-9641
Item Description
- Keywords:
- Pubs id:
-
pubs:966626
- UUID:
-
uuid:5a0b94f4-ab8b-4b40-9c5c-7b46f2c13541
- Local pid:
- pubs:966626
- Source identifiers:
-
966626
- Deposit date:
- 2019-01-28
Terms of use
- Copyright holder:
- Banki et al
- Copyright date:
- 2019
- Notes:
- © 2019 The Authors Immunology & Cell Biology published by John Wiley & Sons Australia, Ltd on behalf of Australasian Society for Immunology Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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