Reduced white matter integrity in sibling pairs discordant for bipolar disorder
Objective: Several lines of evidence indicate that white matter integrity is compromised in bipolar disorder, but the nature, extent, and biological causes remain elusive. To determine the extent to which white matter deficits in bipolar disorder are familial, the authors investigated white matter integrity in a large sample of bipolar patients, unaffected siblings, and healthy comparison subjects.
Method: The authors collected diffusion imaging dat...Expand abstract
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- American Psychiatric Association
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- Copyright © 2013 by the American Psychiatric Association. The full text of this article is not available in ORA.
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