Journal article
Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2
- Abstract:
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Enterovirus 71 (EV71) is a common cause of hand, foot and mouth disease—a disease endemic especially in the Asia-Pacific region1. Scavenger receptor class B member 2 (SCARB2) is the major receptor of EV71, as well as several other enteroviruses responsible for hand, foot and mouth disease, and plays a key role in cell entry2. The isolated structures of EV71 and SCARB2 are known3,4,5,6, but how they interact to initiate infection is not. Here, we report the EV71–SCARB2 complex structure determ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Accepted manuscript, pdf, 278.3KB)
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- Publisher copy:
- 10.1038/s41564-018-0319-z
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Authors
Funding
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Microbiology Journal website
- Volume:
- 4
- Pages:
- 414–419
- Publication date:
- 2018-12-10
- Acceptance date:
- 2018-09-09
- DOI:
- EISSN:
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2058-5276
- Source identifiers:
-
952200
Item Description
- Language:
- English
- Pubs id:
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pubs:952200
- UUID:
-
uuid:5affbd2b-fbc1-4570-a086-0d403cc9b084
- Local pid:
- pubs:952200
- Deposit date:
- 2018-12-13
Terms of use
- Copyright holder:
- Zhou et al
- Copyright date:
- 2018
- Notes:
- © The Author(s), under exclusive licence to Springer Nature Limited 2018. This is the accepted manuscript version of the article. The final version is available online from Springer Nature at: https://doi.org/10.1038/s41564-018-0319-z
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