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Thesis

Cancer cell cycle modulation by metabolic gene expression and role of photoreceptor phosphodiesterase 6H in cancer cell growth

Abstract:

While the deregulation of cancer metabolism through oncogenic signalling, and the effect of the latter on proliferation and cell cycle control are widely studied, little is known on how metabolism in cancer cells leads to cell cycle control and progression. This project aimed to identify metabolic genes whose inhibition causes cell cycle arrest, which would allow further study of candidate genes in the context of cancer metabolism and cell proliferation. The screen was conducted with a cus...

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Division:
MSD
Department:
Oncology
Role:
Author

Contributors

Department:
Oncology
Role:
Supervisor
Role:
Supervisor
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Funding agency for:
Yalaz, C
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Funding agency for:
Yalaz, C
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:5b228db7-b84a-4e75-846a-5c41715bbba4
Deposit date:
2019-10-28

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