Journal article icon

Journal article

Macrophage heterogeneity in the immunopathogenesis of tuberculosis

Abstract:

Macrophages play a central role in tuberculosis, as the site of primary infection, inducers and effectors of inflammation, innate and adaptive immunity, as well as mediators of tissue destruction and repair. Early descriptions by pathologists have emphasized their morphological heterogeneity in granulomas, followed by delineation of T lymphocyte-dependent activation of anti-mycobacterial resistance. More recently, powerful genetic and molecular tools have become available to describe macropha...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.3389/fmicb.2018.01028

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
Role:
Author
More from this funder
Funding agency for:
Marakalala, M
Grant:
206751/Z/17/Z
More from this funder
Funding agency for:
Marakalala, M
Grant:
206751/Z/17/Z
More from this funder
Funding agency for:
Marakalala, M
Grant:
206751/Z/17/Z
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Microbiology Journal website
Volume:
9
Pages:
1028
Publication date:
2018-05-23
Acceptance date:
2018-05-01
DOI:
ISSN:
1664-302X
Source identifiers:
856212
Keywords:
Pubs id:
pubs:856212
UUID:
uuid:5baba224-4192-4c05-b966-47ee68633bca
Local pid:
pubs:856212
Deposit date:
2018-06-08

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP