Journal article
Effect of age and the APOE gene on metabolite concentrations in the posterior cingulate cortex
- Abstract:
-
Proton magnetic resonance spectroscopy (1H-MRS) has provided valuable information about the neurochemical profile of Alzheimer's disease (AD). However, its clinical utility has been limited in part by the lack of consistent information on how metabolite concentrations vary in the normal aging brain and in carriers of apolipoprotein E (APOE) ε4, an established risk gene for AD. We quantified metabolites within an 8 cm3 voxel within the posterior cingulate cortex (PCC)/precuneus in 30 younger (...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Version of record, pdf, 505.3KB)
-
- Publisher copy:
- 10.1016/j.neuroimage.2017.03.031
Authors
Funding
+ US National Institutes of Health
More from this funder
Funding agency for:
Singh-Manoux, A
Grant:
R01AG034454
+ HDH Wills 1965 Charitable Trust
More from this funder
Funding agency for:
Mahmood, A
Filippini, N
Grant:
1117747
1117747
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- NeuroImage Journal website
- Volume:
- 152
- Pages:
- 509-516
- Publication date:
- 2017-03-18
- Acceptance date:
- 2017-03-16
- DOI:
- EISSN:
-
1095-9572
- ISSN:
-
1053-8119
Item Description
- Keywords:
- Pubs id:
-
pubs:686172
- UUID:
-
uuid:5c02d276-a452-4e83-b75f-3fb02c876470
- Local pid:
- pubs:686172
- Source identifiers:
-
686172
- Deposit date:
- 2017-03-16
Terms of use
- Copyright holder:
- © 2017 Suri, et al
- Copyright date:
- 2017
- Notes:
- © 2017 Suri, et al. Published by Elsevier Inc. This is an Open Access article published under a Creative Commons licence, see: https://creativecommons.org/licenses/by/4.0/
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record