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Thesis

Next generation dark-field microscopy: from high-speed single particle tracking to label-free imaging

Abstract:

This thesis details the improvement and implementation of a total internal reflection dark-field scattering microscope, in terms of pushing the boundaries of its sensitivity and spatiotemporal resolution, to study the bending flexibility of DNA on biologically important length scales. Furthermore, by observing the scattering intensity response to the reconfiguration of the electric double layer on a substrate, dark-field microscopy has been brought into the field of label-free imaging, est...

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Authors


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Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Research group:
Kukura group
Oxford college:
Linacre College
Role:
Author
ORCID:
0000-0001-8707-8377

Contributors

Role:
Supervisor
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Programme:
China Scholarship Council-University of Oxford Scholarships
Grant:
201503170234
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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