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Journal article

A meta-analysis of individual participant data reveals an association between circulating levels of IGF-I and prostate cancer risk

Abstract:

The role of insulin-like growth factors (IGFs) in prostate cancer development is not fully understood. To investigate the association between circulating concentrations of IGFs (IGF-I, IGF-II, IGFBP-1, IGFBP-2, IGFBP-3) and prostate cancer risk, we pooled individual participant data from 17 prospective and two cross-sectional studies, including up to 10,554 prostate cancer cases and 13,618 control participants. Conditional logistic regression was used to estimate the odds ratios (ORs) for pro...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1158/0008-5472.CAN-15-1551

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
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More from this funder
Grant:
C8221/A19170
C570/A11691
Publisher:
American Association for Cancer Research Publisher's website
Journal:
Cancer Research Journal website
Volume:
76
Issue:
8
Pages:
2288–2300
Publication date:
2016-02-26
Acceptance date:
2015-12-22
DOI:
EISSN:
1538-7445
ISSN:
0008-5472
Source identifiers:
601697
Keywords:
Pubs id:
pubs:601697
UUID:
uuid:5c694b93-8b2e-4b9e-a200-1db3081a7abc
Local pid:
pubs:601697
Deposit date:
2016-02-11

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