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Value of lipocalin 2 as a potential biomarker for bacterial meningitis

Abstract:

OBJECTIVES: Central nervous system (CNS) infections are common causes of morbidity and mortality worldwide. We aimed to discover protein biomarkers that could rapidly and accurately identify the likely cause of the infections, essential for clinical management and improving outcome.

METHODS: We applied liquid chromatography tandem mass-spectrometry on 45 cerebrospinal fluid (CSF) samples from a cohort of adults with/without CNS infections to discover potential diagnostic biomarkers. ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.cmi.2020.07.006

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Publisher:
Elsevier Publisher's website
Journal:
Clinical Microbiology and Infection Journal website
Volume:
27
Issue:
5
Pages:
724-730
Publication date:
2020-07-10
Acceptance date:
2020-07-04
DOI:
EISSN:
1469-0691
ISSN:
1198-743X
Language:
English
Keywords:
Pubs id:
1119235
Local pid:
pubs:1119235
Deposit date:
2020-07-16

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