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Journal article

Overexpression of the Cytokine BAFF and Autoimmunity Risk.

Abstract:

BACKGROUND: Genomewide association studies of autoimmune diseases have mapped hundreds of susceptibility regions in the genome. However, only for a few association signals has the causal gene been identified, and for even fewer have the causal variant and underlying mechanism been defined. Coincident associations of DNA variants affecting both the risk of autoimmune disease and quantitative immune variables provide an informative route to explore disease mechanisms and drug-targetable path...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1056/NEJMoa1610528

Authors


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Funding agency for:
Todd, JA
Grant:
091157
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Funding agency for:
Todd, JA
Grant:
091157
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Funding agency for:
Cucca, F
Grant:
U1301.2015/AI.1157.BE Prat. 2015-1651
More from this funder
Funding agency for:
Cucca, F
Grant:
U1301.2015/AI.1157.BE Prat. 2015-1651
More from this funder
Funding agency for:
Cucca, F
Grant:
U1301.2015/AI.1157.BE Prat. 2015-1651
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Publisher:
Massachusetts Medical Society Publisher's website
Journal:
New England Journal of Medicine Journal website
Volume:
376
Issue:
17
Pages:
1615-1626
Publication date:
2017-04-27
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Pmid:
28445677
Source identifiers:
692204

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