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Duration of treatment effect should be considered in the design and interpretation of clinical trials: results of a discrete choice experiment

Abstract:
Objective This study examined whether the duration of treatment effect should be considered in a benefit-risk assessment, using a case study of osteoarthritis medications.

Study design and setting A discrete choice experiment was completed by 300 residents of the United Kingdom with hip and/or knee osteoarthritis. In 16 choice tasks, participants selected their preferred option from 2 medications. Medications were described in terms of the effect o... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1177/0272989X19841877

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Centre for Statistics in Medicine
Oxford college:
Wolfson College
Role:
Author
ORCID:
0000-0001-9783-6549
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
Expand authors...
Publisher:
SAGE Publications Publisher's website
Journal:
Medical Decision Making Journal website
Volume:
39
Issue:
4
Pages:
461-473
Publication date:
2019-04-08
Acceptance date:
2019-03-11
DOI:
EISSN:
1552-681X
ISSN:
0272-989X
Source identifiers:
982084
Keywords:
Pubs id:
pubs:982084
UUID:
uuid:5d26995b-c373-486e-a1f2-d84d3cbd9181
Local pid:
pubs:982084
Deposit date:
2019-03-13

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