Thesis
Antibodies directed against AMPA and GABAB receptors in neurological diseases and identification of novel antigen targets
- Abstract:
-
Antibodies directed against AMPAR and GABABR subunits have been implicated in forms of limbic encephalitis (LE), a disease characterised by memory loss and seizures. Patients with LE show clinical improvement with immunomodulatory treatment, suggesting that the associated antibodies are pathogenic. To explore further the AMPAR and GABABR antibodies, an in house cell based assay (CBA) was established for screening and potential pathogenicity was explored using a series...
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Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:5d3eb5fa-9f51-4415-92bd-2d7c795aa51c
- Local pid:
- ora:10143
- Deposit date:
- 2015-02-20
Terms of use
- Copyright holder:
- Dr. Anjan Nibber
- Copyright date:
- 2014
- Notes:
- This thesis is not currently available in ORA.
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