Thesis
Investigations on anti-IGF-1R therapy response in a colorectal cancer cell line panel
- Abstract:
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Therapies targeting the type 1 insulin like growth factor receptor (IGF-1R) have so far failed to show significant benefit for colorectal cancer (CRC) patients in large clinical trials, emphasising the importance of identifying biomarkers for therapy response and developing rational combination therapies.
In this thesis, a large panel of 82 colorectal cancer cell lines was used to discover and validate associations between anti-IGF-1R therapy response, gene mutations and gene expres...
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Funding
Bibliographic Details
- Type of award:
- MSc by Research
- Level of award:
- Masters
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:5d721125-0166-42bc-9c95-188902025bb7
- Deposit date:
- 2016-12-01
Terms of use
- Copyright holder:
- Puschhof, J
- Copyright date:
- 2016
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