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Thesis

The design and development of an HIV-1 vaccine to elicit a broadly neutralising antibody response

Abstract:

Despite 30 years of research, a prophylactic vaccine against HIV-1 is still lacking and is urgently needed in order to control the global AIDS pandemic. The discovery of broadly neutralising antibodies (BNAbs) was an important step for HIV-1 research but no vaccine candidate tested so far has been able to reproduce responses containing such antibodies, and it remains unclear how this could be achieved via immunisation. In this thesis, I attempted to explore this gap of knowledge in two ways. ...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
Human Immunology Unit
Oxford college:
Green Templeton College
Role:
Author
More by this author
Division:
MSD
Department:
NDM
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:5de89b0d-a0bd-47e4-b577-87adf68bfb69
Local pid:
ora:8572
Deposit date:
2014-06-10

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