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Maintaining protection against invasive bacteria with protein - polysaccharide conjugate vaccines

Abstract:

Polysaccharide-encapsulated organisms are the leading cause of bacterial meningitis and pneumonia in children. The use of protein-polysaccharide conjugate vaccines in developed countries over the past two decades has markedly decreased the burden of disease and mortality from these organisms through direct protection of the immunized and through herd immunity. In the next decade, the widespread use of conjugate vaccines in the developing world should prevent millions of deaths. In this Scienc...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/nri2494

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Research group:
Oxford Vaccine Goup
Role:
Author
More by this author
Institution:
"University of Melbourne, Australia", "University of Oxford"
Research group:
Oxford Vaccine Group
Department:
Medical Sciences Division - Paediatrics,Department of
Role:
Author
More by this author
Institution:
"Edward Jenner Institute for Vaccine Research, Newbury, UK"
Role:
Author
Publisher:
Nature Publishing Group Publisher's website
Journal:
Nature Reviews Immunology Journal website
Volume:
9
Pages:
213-220
Publication date:
2009-03-01
DOI:
EISSN:
1474-1741
ISSN:
1474-1733
Language:
English
Subjects:
UUID:
uuid:5e106cc4-4788-4a0a-b284-7f24c91aad34
Local pid:
ora:3248
Deposit date:
2010-01-20

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