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Exploration of proton transfer pathways in the oxygen-tolerant [NiFe]-hydrogenase from Escherichia coli

Abstract:

Hydrogenases catalyse the interconversion of molecular hydrogen with protons and electrons. Thus, they are of significance due to the growing interest in a hydrogen economy, which would serve to replace fossil fuels. Hyd-1 is a [NiFe]-hydrogenase from Escherichia coli and, unlike many hydrogenases, it is capable of hydrogenases oxidation in the presence of oxygen. Understanding the mechanism of hydrogen activation by Hyd-1 is, therefore, paramount to the rational design of synthetic analog...

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Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author

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Supervisor
Engineering & Physical Sciences Research Council More from this funder
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
UUID:
uuid:5e6aa669-00c1-41fa-a5e7-de9edd7ddde9
Deposit date:
2018-06-26

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