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Thesis

Role of mutual information for predicting contact residues in proteins

Abstract:

Mutual Information (MI) based methods are used to predict contact residues within proteins and between interacting proteins. There have been many high impact papers citing the successful use of MI for determining contact residues in a particular protein of interest, or in certain types of proteins, such as homotrimers. In this dissertation we have carried out a systematic study to assess if this popularly employed contact prediction tool is useful on a global scale.

After testing ori...

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Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Research group:
Oxford Protein Informatics Group
Oxford college:
St Anne's College
Role:
Author

Contributors

Division:
MPLS
Department:
Statistics
Role:
Supervisor
Division:
MPLS
Department:
Statistics
Role:
Supervisor
More from this funder
Funding agency for:
Gomes, M
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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