Thesis
The role of astrocytes in brain metastasis
- Abstract:
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Brain metastasis is a significant clinical problem, and 20-40% of cancer patients will develop metastatic spread to the brain.There remains, however, an urgent need to better understand the pathogenesis of brain metastasis and, in particular, the contribution of the tumour microenvironment. Astrocytes are activated in response to metastatic growth and in vitro studies suggest that this activation promotes tumour growth and invasion. However, the result of astrocyte activation ha...
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Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:60efc7bd-4f00-4e84-a964-c4ef55009dfb
- Local pid:
- ora:11894
- Deposit date:
- 2015-07-27
Terms of use
- Copyright holder:
- O'Brien, E
- Copyright date:
- 2014
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