Internet publication icon

Internet publication

Sex- and age-specific associations between cardiometabolic risk and white matter brain age in the UK Biobank cohort

Abstract:

Cardiometabolic risk factors (CMRs) are associated with accelerated brain aging and increased risk for sex-dimorphic illnesses such as Alzheimer’s Disease (AD). Yet, it is unknown how CMRs interact with sex and apolipoprotein E-ε4 (APOE4), a known genetic risk factor for AD, to influence brain age across different life stages. Using age prediction based on multi-shell diffusion-weighted imaging data in 21,308 UK Biobank participants, we investigated whether associations between white matter B...

Expand abstract
Publication status:
Published
Peer review status:
Not peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.31234/osf.io/7xcun

Authors


More by this author
Role:
Author
ORCID:
0000-0003-3207-0700
More by this author
Role:
Author
ORCID:
0000-0002-5136-8302
More by this author
Role:
Author
ORCID:
0000-0001-9393-5857
Expand authors...
Host title:
Center for Open Science
Publication date:
2021-12-14
DOI:
Language:
English
Keywords:
Pubs id:
1225463
Local pid:
pubs:1225463
Deposit date:
2021-12-16

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP