Journal article
Rapid and efficient differentiation of functional motor neurons from human iPSC for neural injury modelling
- Abstract:
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Primary rodent neurons and immortalised cell lines have overwhelmingly been used for in vitro studies of traumatic injury to peripheral and central neurons, but have some limitations of physiological accuracy. Motor neurons (MN) derived from human induced pluripotent stem cells (iPSCs) enable the generation of cell models with features relevant to human physiology. To facilitate this, it is desirable that MN protocols both rapidly and efficiently differentiate human iPSCs into electrophysiolo...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 3.2MB)
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- Publisher copy:
- 10.1016/j.scr.2018.09.006
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Authors
Funding
+ Engineering and Physical Sciences Research Council
More from this funder
Funding agency for:
Bianchi, F
Grant:
1514540
China
Regenerative Medicine Limited
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Stem Cell Research Journal website
- Volume:
- 32
- Pages:
- 126-134
- Publication date:
- 2018-09-26
- Acceptance date:
- 2018-09-10
- DOI:
- EISSN:
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1876-7753
- ISSN:
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1873-5061
- Source identifiers:
-
920126
Item Description
- Keywords:
- Pubs id:
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pubs:920126
- UUID:
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uuid:611d9e2c-e262-47b2-892b-7b606e24319c
- Local pid:
- pubs:920126
- Deposit date:
- 2018-09-17
Terms of use
- Copyright holder:
- Bianchi et al
- Copyright date:
- 2018
- Notes:
- © 2018 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license
- Licence:
- CC Attribution (CC BY)
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