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Journal article

Saliva testing for human papilloma virus in oropharyngeal squamous cell carcinoma: A diagnostic accuracy study.

Abstract:

Background

New cases of oropharyngeal squamous cell carcinoma (OPSCC) are routinely tested for HPV. HPV in saliva can be detected with PCR, but its clinical applicability in the context of OPSCC remains unknown.

Methods

Forty-six consecutive patients diagnosed with OPSCC had pre-treatment saliva specimens collected. PCR for HPV on saliva was compared to p16 IHC and HPV DNA in situ hybridisation (ISH) on surgical biopsies.

Results

The sensitivity an...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/coa.12917

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Role:
Author
ORCID:
0000-0001-8654-6888
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
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Oxfordshire Health Services Research Committee More from this funder
National Institute for Health Research More from this funder
Publisher:
Wiley Publisher's website
Journal:
Clinical Otolaryngology Journal website
Publication date:
2017-06-01
Acceptance date:
2017-06-10
DOI:
EISSN:
1749-4486
ISSN:
1749-4478
Pmid:
28620984
Source identifiers:
702545
Language:
English
Keywords:
Pubs id:
pubs:702545
UUID:
uuid:61358c7f-6fb5-4bcb-842f-6fdcd03c5e63
Local pid:
pubs:702545
Deposit date:
2017-12-18

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