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Protein engineering to capture and kill cancer cells

Abstract:

The formation of protein assemblies to carry out sophisticated functions is constantly gaining attention in nano-biotechnology. However protein assemblies are often linked through non-covalent interactions, limiting the stability of the complexes and the resilience to forces. Force resistance is crucial for magnetic isolation of circulating tumour cells (CTCs), when a specific protein interaction must withstand the forces pulling a captured cell in the magnetic field. CTCs are present in t...

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Oxford college:
Merton College
Role:
Author

Contributors

Department:
Department of Biochemistry
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:620a951d-a59b-4a33-b071-d758964e6303
Deposit date:
2016-02-08

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